Type 1 autoimmune pancreatitis

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Type 1 autoimmune pancreatitis

Before the concept of autoimmune pancreatitis (AIP) was established, this form of pancreatitis had been recognized as lymphoplasmacytic sclerosing pancreatitis or non-alcoholic duct destructive chronic pancreatitis based on unique histological features. With the discovery in 2001 that serum IgG4 concentrations are specifically elevated in AIP patients, this emerging entity has been more widely ...

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Type 2 autoimmune pancreatitis

Histopathology of type 2 AIP The pancreas of patients with type 2 AIP is often only focally involved. The region that seems to be most often affected is the pancreatic head including the pancreatic portion of the distal bile duct. As in type 1 AIP, the outstanding histologic feature is a periductal lymphoplasmacytic infiltrate usually affecting some or all of the medium sized ducts (Figure 1). ...

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Regulatory T Cells in Type 1 Autoimmune Pancreatitis

Autoimmune pancreatitis (AIP) is a newly recognized pancreatic disorder. Recently, International Consensus Diagnostic Criteria for AIP (ICDC) was published. In this ICDC, AIP was classified into Type 1 and Type 2. Patients with Type 1 AIP have several immunologic and histologic abnormalities specific to the disease, including increased levels of serum IgG4 and storiform fibrosis with infiltrati...

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A non-invasive screening technique for type 1 autoimmune pancreatitis

INTRODUCTION Type 1 autoimmune pancreatitis (AIP) is the pancreatic manifestation of a systemic fibroinflammatory IgG4-related disease. Accurate diagnosis of AIP can avoid major hepatobiliary and pancreatic surgery as it respond dramatically to corticosteroid therapy. AIM This research investigated the feasibility of using peripheral blood cell immunohistochemistry, serum IgG4, T-cell recepto...

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Association of newly diagnosed type 1 diabetes and autoimmune pancreatitis

Autoimmune pancreatitis is a new nosological entity in which a lymphocytic infiltration of the exocrine pancreas is involved. The concomitant onset of autoimmune pancreatitis and type 1 diabetes has been recently described suggesting a unique immune disturbance that compromises the pancreatic endocrine and exocrine functions. We report a case of type1 diabetes onset associated with an autoimmun...

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ژورنال

عنوان ژورنال: Advances in Digestive Medicine

سال: 2017

ISSN: 2351-9800

DOI: 10.1002/aid2.12041